Coach: Don Shula (12-2)
StatisticsRoster
The of the ended the season with a record of wins and losses, Don Shula coached the team.
Regular Season Points For: 428
Regular Season Points Against: 225
| Date | Game | Res | Home | Road | Record | ||
| September 13, 1964 | Baltimore Colts 24 at Minnesota Vikings 34 | L | 0-0-0 | 0-1-0 | 0-1-0 | ||
| September 20, 1964 | Baltimore Colts 21 at Green Bay Packers 20 | W | 0-0-0 | 1-1-0 | 1-1-0 | ||
| September 27, 1964 | Chicago Bears 0 at Baltimore Colts 52 | W | 1-0-0 | 1-1-0 | 2-1-0 | ||
| October 4, 1964 | St. Louis Cardinals 20 at Baltimore Colts 35 | W | 2-0-0 | 1-1-0 | 3-1-0 | ||
| October 12, 1964 | St. Louis Cardinals 27 at Baltimore Colts 47 | W | 3-0-0 | 1-1-0 | 4-1-0 | ||
| October 18, 1964 | Green Bay Packers 21 at Baltimore Colts 24 | W | 4-0-0 | 1-1-0 | 5-1-0 | ||
| October 25, 1964 | Baltimore Colts 34 at Detroit Lions 0 | W | 4-0-0 | 2-1-0 | 6-1-0 | ||
| November 1, 1964 | San Francisco 49ers 7 at Baltimore Colts 37 | W | 5-0-0 | 2-1-0 | 7-1-0 | ||
| November 8, 1964 | Baltimore Colts 40 at Chicago Bears 24 | W | 5-0-0 | 3-1-0 | 8-1-0 | ||
| November 15, 1964 | Minnesota Vikings 14 at Baltimore Colts 17 | W | 6-0-0 | 3-1-0 | 9-1-0 | ||
| November 22, 1964 | Baltimore Colts 24 at Los Angeles Rams 7 | W | 6-0-0 | 4-1-0 | 10-1-0 | ||
| November 29, 1964 | Baltimore Colts 14 at San Francisco 49ers 3 | W | 6-0-0 | 5-1-0 | 11-1-0 | ||
| December 6, 1964 | Detroit Lions 31 at Baltimore Colts 14 | L | 6-1-0 | 5-1-0 | 11-2-0 | ||
| December 13, 1964 | Washington Redskins 17 at Baltimore Colts 45 | W | 7-1-0 | 5-1-0 | 12-2-0 | ||
| December 27, 1964 | Baltimore Colts 0 at Cleveland Browns 27 | L | 0-0-0 | 0-1-0 | 0-1-0 | NFL Championship |